Top 10 Cancer Treatment Centers in Indiana
Navigating a cancer diagnosis can feel overwhelming, especially when facing a terminal illness. Knowing you have access to the best possible care is crucial. In Indiana, several cancer treatment centers offer advanced treatments, cutting-edge research, and compassionate support. This list highlights ten of the top cancer treatment centers in Indiana, offering hope and comprehensive care to those facing challenging diagnoses. We understand the urgency and emotional weight of this search, and we aim to provide you with valuable information to make informed decisions about cancer treatment centers in Indiana.
This list is not exhaustive and is intended to provide a starting point for your research. It is essential to consult with your physician or oncologist to determine the most appropriate treatment center and plan for your specific situation.
Quick Reference Comparison
Compare key features at a glance to help narrow your search
| Cancer Center | NCI Status | Top Specialties | Clinical Trials | Network | Best For |
|---|---|---|---|---|---|
| IU Simon Cancer Center (Indianapolis) | ✓ Comprehensive | Immunotherapy, CAR T-cell, Proton Therapy | Extensive (300+) | Single Location | Complex/Rare Cancers |
| Parkview Cancer Institute (Fort Wayne) | — | Breast, Lung, Prostate | Available | Multiple Locations | Northeast IN Access |
| Franciscan Health Cancer (Statewide) | — | Breast, Lung, GI Cancers | Limited | 15+ Locations | Community-Based Care |
| Community Health Network (Indianapolis) | — | Breast, Lung, Colorectal | Available | Multiple Locations | Integrated Care Model |
| Ascension St. Vincent (Statewide) | — | Breast, Lung, Hematology | Limited | Multiple Locations | Faith-Based Care |
| Deaconess Cancer Services (Evansville) | — | Breast, Lung, Prostate | Limited | Single Location | Southern IN Region |
| Goshen Center for Cancer Care (Goshen) | — | Breast, Lung, Colorectal | Limited | Single Location | Northern IN Region |
| Reid Health Cancer Center (Richmond) | — | Breast, Lung, Hematology | Limited | Single Location | East Central IN |
| Lutheran Hospital Cancer (Fort Wayne) | — | Breast, Lung, Prostate | Limited | Single Location | Fort Wayne Area |
| Community Hospital North (Indianapolis) | — | Breast, Lung, Colorectal | Available | Multiple Locations | North Indianapolis |
Legend: ✓ Comprehensive = NCI-designated Comprehensive Cancer Center (highest designation) | ✓ Designated = NCI-designated Cancer Center | — = Not NCI-designated
1. Indiana University Melvin and Bren Simon Comprehensive Cancer Center (Indianapolis, IN)
The IU Simon Comprehensive Cancer Center is Indiana's only National Cancer Institute-designated Comprehensive Cancer Center, representing the highest level of cancer care in the United States and the pinnacle of cancer treatment in Indiana.
Strengths
- NCI-designated Comprehensive Cancer Center (1 of approximately 50 nationwide)
- Over 300 active clinical trials offering access to cutting-edge treatments not yet widely available
- Houses one of the nation's advanced proton therapy centers for precise radiation treatment
- Pioneer in CAR T-cell immunotherapy and cellular therapy programs
- Consistently ranked among top cancer hospitals by U.S. News & World Report
- Multidisciplinary tumor boards meet weekly to review complex cases collaboratively
- Partnership with Indiana University School of Medicine provides access to latest research
Specialties
- Hematologic malignancies (leukemia, lymphoma, myeloma) with dedicated bone marrow transplant unit
- Breast cancer center with genetics program and high-risk screening services
- Thoracic oncology program for lung and esophageal cancers
- Precision medicine utilizing comprehensive genomic profiling for personalized treatment
- Immunotherapy and cellular therapy programs including CAR T-cell therapy
- Gastrointestinal and pancreatic cancer programs with specialized surgical expertise
- Neuro-oncology program for brain tumors and central nervous system cancers
Patient Support Areas
- Comprehensive psychosocial oncology services including individual counseling and support groups
- Financial counselors to help navigate insurance and identify assistance programs
- Integrative medicine services (acupuncture, massage therapy, meditation classes)
- Dedicated patient navigators assigned to each patient to coordinate complex care
- Nutritional counseling with registered oncology dietitians
- Palliative care team integrated from diagnosis through survivorship
- Spiritual care services and chaplaincy support available 24/7
Things to Consider
- High patient volume may result in 2-3 week wait for initial consultations
- Complex academic medical center environment can feel overwhelming for some patients
- Parking challenges in Indianapolis campus location (valet services available but costly)
- Most advanced treatments (proton therapy, certain clinical trials) only available at main Indianapolis location
- May require multiple visits for second opinions and treatment planning before beginning therapy
NCI-designated Comprehensive Cancer Centers meet the highest standards for cancer research and treatment. Only about 50 centers nationwide hold this prestigious designation, ensuring access to the latest clinical trials and innovative therapies that may not be available at other facilities.
2. Parkview Cancer Institute (Fort Wayne, IN)
Parkview Cancer Institute provides comprehensive cancer care to northeastern Indiana with a focus on patient-centered treatment and advanced technology across multiple convenient locations.
Strengths
- Largest integrated cancer program in northeastern Indiana serving 20-county region
- American College of Surgeons Commission on Cancer accreditation ensuring quality standards
- State-of-the-art PET/CT imaging and advanced radiation therapy technologies
- Strong emphasis on multidisciplinary care coordination and tumor boards
- Participation in national clinical trial networks through research consortiums
- Same-day appointments available for urgent cancer concerns
Specialties
- Comprehensive breast cancer center with genetic counseling and surgical options
- Lung cancer screening program and thoracic oncology services
- Prostate cancer treatment with advanced radiation and surgical options
- Colorectal cancer program with minimally invasive surgical techniques
- Hematology and bone marrow disorders treatment center
- Gynecologic oncology services with specialized surgical expertise
Patient Support Areas
- Cancer rehabilitation services including physical and occupational therapy
- Nutritional counseling and dietary support throughout treatment
- Social work services and counseling for emotional support
- Financial counseling and assistance with insurance navigation
- Survivorship programs focusing on life after treatment
- Support groups for patients and caregivers (in-person and virtual)
- Pain management and palliative care specialists integrated into treatment teams
Things to Consider
- Not NCI-designated, so research focus and clinical trial access more limited than IU Simon
- Complex or rare cancers may require referral to IU Simon in Indianapolis
- Some specialized treatments not available (no proton therapy, limited immunotherapy trials)
- Geographic location requires travel for patients outside northeastern Indiana region
- Wait times for certain specialists can extend 2-4 weeks during high-volume periods
3. Franciscan Health Cancer Centers (Multiple Locations Statewide)
Franciscan Health operates comprehensive cancer centers at 15+ locations throughout Indiana, providing faith-based compassionate care close to home with convenient community access.
Strengths
- Extensive statewide network with 15+ locations reducing travel burden for patients
- American College of Surgeons Commission on Cancer accreditation at major centers
- Participation in national clinical trials through cooperative group networks
- Advanced radiation therapy including IMRT, IGRT, and stereotactic techniques
- Comprehensive breast centers with same-day biopsy results at select locations
- Integration with Franciscan Health system allows coordinated care across specialties
Specialties
- Breast cancer comprehensive screening, diagnosis, and treatment programs
- Lung cancer program with low-dose CT screening and advanced treatments
- Gastrointestinal cancers including colorectal, pancreatic, and hepatobiliary
- Gynecologic oncology services with minimally invasive surgical options
- Hematologic malignancies and blood disorder treatments
- Head and neck cancer programs at select locations
Patient Support Areas
- Nurse navigation services to guide patients through treatment journey
- Spiritual care and chaplaincy services reflecting Franciscan mission
- Support groups at multiple locations for various cancer types
- Nutritional counseling and wellness programs
- Financial counseling and assistance program navigation
- Palliative care consultations available at all locations
- Patient education resources and cancer resource libraries
Things to Consider
- Service levels and specialist availability vary significantly across 15+ locations
- Most complex cases require referral to Indianapolis or regional hubs
- Not NCI-designated, limiting access to cutting-edge research and rare trials
- Faith-based care philosophy may not align with all patients' preferences
- Some advanced technologies only available at larger Franciscan facilities
- Clinical trial availability more limited compared to academic centers
4. Community Health Network Cancer Centers (Indianapolis Metro)
Community Health Network operates multiple cancer centers across the Indianapolis metropolitan area, offering comprehensive care through an integrated health system model.
Strengths
- Integrated care model ensures seamless coordination between specialists and services
- Multiple convenient locations throughout Indianapolis reducing travel time
- Advanced imaging and diagnostic technologies at all major centers
- Participation in national clinical trial networks providing access to new therapies
- Genetic counseling and risk assessment programs for hereditary cancers
- Strong emphasis on patient experience and satisfaction metrics
Specialties
- Comprehensive breast cancer program with genetic testing and reconstruction options
- Lung cancer screening and treatment with advanced thoracic surgery
- Colorectal cancer program with colonoscopy and surgical services
- Gynecologic oncology with minimally invasive robotic surgery
- Hematology/oncology services for blood cancers and disorders
- Radiation oncology with advanced IMRT and IGRT techniques
Patient Support Areas
- Patient navigation services coordinating all aspects of cancer care
- Psychosocial support including counseling and therapy services
- Nutritional counseling with registered dietitians specializing in oncology
- Financial counseling and assistance with treatment cost management
- Support groups for patients and caregivers at multiple locations
- Survivorship programs addressing long-term effects and wellness
- Integrative medicine options including yoga and meditation classes
Things to Consider
- Not NCI-designated, limiting access to most innovative research protocols
- Complex or rare cancers may benefit from evaluation at IU Simon
- Clinical trial portfolio smaller than academic comprehensive cancer centers
- Some specialized treatments may require referral to tertiary centers
- Insurance acceptance and billing through larger health system can be complex
5. Ascension St. Vincent Cancer Care (Multiple Locations Statewide)
Ascension St. Vincent provides cancer treatment services at multiple locations throughout Indiana as part of a national healthcare system, offering faith-based compassionate care.
Strengths
- Part of large national Ascension system allowing access to extensive resources
- Multiple locations across Indiana providing convenient regional access
- Advanced diagnostic imaging and radiation therapy technologies
- Experienced multidisciplinary oncology teams at major centers
- Patient-centered approach emphasizing communication and shared decision-making
- Electronic health records integration improves care coordination across locations
Specialties
- Breast cancer comprehensive screening, treatment, and reconstruction programs
- Lung cancer program with screening and advanced treatment options
- Hematologic malignancies including leukemia and lymphoma treatments
- Gastrointestinal cancers with medical and surgical oncology services
- Gynecologic cancers with specialized surgical expertise
- Radiation oncology services with modern linear accelerators
Patient Support Areas
- Oncology nurse navigation to coordinate complex care pathways
- Social work services addressing emotional and practical needs
- Spiritual care and chaplaincy reflecting Catholic healthcare mission
- Financial counseling and assistance with insurance and payment plans
- Support groups at select locations for patients and families
- Palliative care consultations integrated throughout treatment
- Patient education programs and wellness resources
Things to Consider
- Service quality and specialist availability varies across network locations
- Not NCI-designated as an institution, limiting cutting-edge research access
- Most complex cases require coordination with or referral to larger centers
- Faith-based healthcare philosophy influences care approach and certain services
- Clinical trial availability limited compared to academic medical centers
- Some locations may have longer wait times for specialist appointments
6. Deaconess Cancer Services (Evansville, IN)
Deaconess Cancer Services provides comprehensive cancer care to southern Indiana and surrounding regions with a focus on community-based accessible treatment.
Strengths
- Largest cancer program in southwestern Indiana serving tri-state area
- American College of Surgeons Commission on Cancer accreditation
- Advanced radiation therapy including IMRT, IGRT, and 3D conformal techniques
- Participation in cooperative group clinical trials through national networks
- Multidisciplinary tumor boards review all complex cases weekly
- Strong community engagement and cancer prevention programs
Specialties
- Breast cancer comprehensive program with surgical and reconstruction options
- Lung cancer screening and treatment with thoracic surgery expertise
- Prostate cancer treatment with radiation and surgical options
- Colorectal cancer program with advanced colonoscopy and surgery
- Hematology services for blood cancers and disorders
- Gynecologic cancer treatment with surgical oncology
Patient Support Areas
- Patient navigation services guiding patients through treatment process
- Psychosocial support and counseling for patients and families
- Nutritional counseling services throughout treatment journey
- Financial counseling and assistance with treatment costs
- Support groups for various cancer types and caregiver support
- Survivorship programs focusing on wellness after treatment
- Cancer resource center with educational materials and information
Things to Consider
- Not NCI-designated, limiting access to most cutting-edge research
- Geographic location requires significant travel for patients outside southern Indiana
- Complex or rare cancers may require referral to IU Simon or out-of-state centers
- Fewer clinical trial options compared to comprehensive academic centers
- Some advanced technologies not available (no proton therapy)
- Subspecialty oncology expertise more limited than larger academic centers
7. Goshen Center for Cancer Care (Goshen, IN)
Goshen Center for Cancer Care serves northern Indiana with comprehensive cancer services and a commitment to integrative, patient-centered treatment approaches.
Strengths
- American College of Surgeons Commission on Cancer accredited facility
- Integration with Goshen Health system allows coordinated multidisciplinary care
- Emphasis on integrative oncology combining conventional and supportive therapies
- Advanced radiation therapy technologies including IMRT and image guidance
- Strong focus on patient education and empowerment in treatment decisions
- Participation in clinical trials through collaborative research networks
Specialties
- Breast cancer comprehensive screening, diagnosis, and treatment programs
- Lung cancer services with screening and medical oncology
- Colorectal cancer program with surgical and medical oncology
- Hematologic cancers and blood disorder treatments
- Gynecologic cancer services with surgical expertise
- Radiation oncology with advanced treatment planning
Patient Support Areas
- Integrative medicine services including acupuncture, massage, and mind-body therapies
- Nutritional counseling emphasizing nutrition's role in cancer care
- Social work and counseling services for emotional support
- Financial counseling and assistance program navigation
- Support groups for patients and caregivers
- Palliative care services integrated into treatment plans
- Wellness programs focusing on exercise and stress management
Things to Consider
- Smaller community-based program with fewer resources than academic centers
- Not NCI-designated, limiting access to innovative research protocols
- Complex or rare cancers may require consultation or referral to larger centers
- Limited clinical trial portfolio compared to comprehensive cancer centers
- Some specialized treatments may not be available locally
- Geographic location requires travel for patients outside northern Indiana region
8. Reid Health Cancer Center (Richmond, IN)
Reid Health Cancer Center provides comprehensive cancer care to east central Indiana and west central Ohio, bringing advanced treatment closer to home for rural communities.
Strengths
- Serves large geographic region with limited other cancer care options
- American College of Surgeons Commission on Cancer accreditation
- Advanced diagnostic imaging including PET/CT and MRI services
- Experienced oncology team with multidisciplinary approach
- Strong emphasis on personalized treatment plans and patient education
- Community-focused care with attention to individual patient needs
Specialties
- Breast cancer screening, diagnosis, and comprehensive treatment
- Lung cancer program with medical and radiation oncology
- Hematology services for blood cancers and disorders
- Gastrointestinal cancers including colorectal and pancreatic
- Prostate cancer treatment with radiation and medical oncology
- Gynecologic cancer services with surgical options
Patient Support Areas
- Patient navigation services coordinating care across specialties
- Social work services addressing emotional and practical challenges
- Nutritional counseling supporting dietary needs during treatment
- Financial counseling and assistance with insurance and costs
- Support groups providing community connection and peer support
- Palliative care consultations for symptom management
- Patient education resources and cancer information library
Things to Consider
- Smaller regional program with fewer specialized services than urban centers
- Not NCI-designated, limiting access to cutting-edge research trials
- Complex or rare cancers may require referral to IU Simon or other centers
- Limited clinical trial availability compared to academic medical centers
- Some advanced treatments require travel to Indianapolis or other cities
- Specialist availability may be more limited than larger comprehensive centers
9. Lutheran Hospital Cancer Center (Fort Wayne, IN)
Lutheran Hospital Cancer Center, part of the Parkview Health system, provides comprehensive cancer care to the Fort Wayne area with advanced technology and compassionate support.
Strengths
- American College of Surgeons Commission on Cancer accredited program
- Advanced radiation therapy including IMRT, IGRT, and stereotactic techniques
- Integration with Parkview Health system allows coordinated care access
- Multidisciplinary tumor boards review cases collaboratively
- Experienced medical oncology and hematology teams
- Strong focus on patient comfort and supportive care throughout treatment
Specialties
- Breast cancer comprehensive screening and treatment programs
- Lung cancer services with diagnostic and treatment capabilities
- Prostate cancer treatment with radiation and medical oncology
- Colorectal cancer program with surgical and medical oncology
- Hematologic malignancies and blood disorder treatments
- Gynecologic cancer services with surgical expertise
Patient Support Areas
- Patient navigation services guiding patients through cancer journey
- Psychosocial support and counseling for patients and families
- Nutritional counseling with registered dietitians
- Financial counseling and assistance with treatment costs
- Support groups for various cancer types
- Palliative care services for symptom management and quality of life
- Cancer education programs and wellness resources
Things to Consider
- Part of larger Parkview system, so coordination with other Parkview facilities may be needed
- Not NCI-designated, limiting access to most innovative research
- Clinical trial availability more limited than academic comprehensive centers
- Some specialized treatments may require travel to main Parkview Cancer Institute
- Complex or rare cancers may benefit from evaluation at tertiary centers
- Geographic location requires travel for patients outside Fort Wayne area
10. Community Hospital North Cancer Center (Indianapolis, IN)
Community Hospital North Cancer Center provides comprehensive cancer care as part of the Community Health Network, offering convenient access for residents of northern Indianapolis and surrounding communities.
Strengths
- Part of integrated Community Health Network system ensuring coordinated care
- Convenient location in northern Indianapolis suburbs
- Advanced diagnostic and treatment technologies
- Participation in clinical trials through network research programs
- Experienced multidisciplinary oncology teams
- Strong emphasis on patient experience and satisfaction
Specialties
- Breast cancer comprehensive screening, diagnosis, and treatment
- Lung cancer program with advanced imaging and treatment options
- Colorectal cancer screening and treatment services
- Hematology/oncology for blood cancers and disorders
- Gynecologic cancer treatment with surgical options
- Radiation oncology with modern treatment technologies
Patient Support Areas
- Patient navigation coordinating appointments and treatment schedules
- Psychosocial support services including counseling
- Nutritional counseling with oncology-specialized dietitians
- Financial counseling and assistance navigating insurance
- Support groups for patients and caregivers
- Survivorship programs addressing post-treatment wellness
- Integrative medicine options at select Community Health locations
Things to Consider
- Not NCI-designated, limiting access to most cutting-edge research
- Complex or rare cancers may require referral to IU Simon
- Clinical trial portfolio smaller than academic cancer centers
- Some highly specialized treatments available only at other network locations
- As part of larger system, care coordination requires communication across facilities
- Subspecialty oncology expertise more limited than comprehensive cancer centers
When choosing a cancer treatment center in Indiana, prioritize centers with specific expertise in your cancer type. For rare or complex cancers, IU Simon Comprehensive Cancer Center offers the most clinical trial options and cutting-edge treatments. Community centers like Parkview, Franciscan Health, and Community Health Network provide excellent care for common cancers with greater convenience. Don't hesitate to seek second opinions or consult multiple centers before making your decision.
Moving Forward: Finding the Right Fit
Choosing a cancer treatment center is a deeply personal decision that should balance medical expertise, convenience, and personal comfort. Consider these key factors:
- Cancer Type Expertise: Does the center specialize in your specific cancer type and stage?
- NCI Designation: For complex or rare cancers, IU Simon's NCI Comprehensive designation offers significant advantages
- Clinical Trials: Access to trials can provide cutting-edge treatment options not yet widely available
- Location: Balance travel burden against specialized expertise needs for your situation
- Support Services: Comprehensive support improves quality of life during treatment journey
- Insurance Coverage: Verify coverage before committing to a center to avoid unexpected costs
We understand that this is a challenging time, and we are here to support you. Explore our financial assistance resources and grants directory to help manage treatment costs. Our comprehensive guide for newly diagnosed patients can help you navigate the next steps in your cancer journey.
Frequently Asked Questions
Q: What makes IU Simon Comprehensive Cancer Center different from other Indiana cancer centers?
A: As Indiana's only NCI-designated Comprehensive Cancer Center, IU Simon meets the highest standards for cancer research, treatment, and education. This designation ensures access to over 300 clinical trials, innovative therapies, and multidisciplinary teams of specialists that may not be available at other Indiana centers. It's particularly valuable for rare, complex, or aggressive cancers.
Q: How do I choose between cancer centers in Indianapolis and regional centers throughout Indiana?
A: Consider your specific cancer type and complexity. For rare or aggressive cancers, IU Simon's NCI designation may provide significant advantages. For more common cancers like breast, lung, or prostate cancer, quality regional centers like Parkview, Franciscan Health, or Community Health Network offer excellent care closer to home, reducing travel stress and maintaining support systems.
Q: Will my insurance cover treatment at these Indiana cancer centers?
A: Most Indiana insurance plans are accepted at these centers, but coverage varies by plan and specific treatments. Contact the cancer center's financial counseling department before your first appointment to verify coverage and understand potential out-of-pocket costs. Ask specifically about coverage for clinical trials if you're interested in participating.
Q: Can I participate in clinical trials at Indiana cancer centers?
A: Yes, especially at IU Simon Comprehensive Cancer Center, which has the most extensive clinical trial portfolio in Indiana with over 300 active trials. Other centers participate in trials through collaborative networks like the National Cancer Institute's cooperative groups. Ask your oncologist about available trials for your specific cancer type.
Q: What is proton therapy and where is it available in Indiana?
A: Proton therapy is an advanced form of radiation therapy that precisely targets tumors while minimizing damage to surrounding healthy tissue. IU Simon Comprehensive Cancer Center in Indianapolis offers proton therapy in Indiana. It's particularly beneficial for certain cancers near critical organs, pediatric cancers, and cases where preserving healthy tissue is crucial.
Q: Should I travel to Indianapolis for cancer treatment or stay closer to home?
A: This depends on your cancer type, stage, and treatment complexity. For complex, rare, or aggressive cancers, specialized care at IU Simon may be worth the travel. For more common cancers, many regional centers throughout Indiana provide excellent care. Discuss this decision with your oncologist, considering both medical needs and quality of life factors like travel burden and support systems.
Q: What supportive care services should I expect at an Indiana cancer center?
A: Comprehensive cancer centers should offer pain management, nutritional counseling, mental health support, social work services, financial counseling, palliative care, support groups, and patient navigation. These services are essential for maintaining quality of life during treatment. All centers on this list offer basic support services, but IU Simon and larger regional centers typically offer more extensive programs.
Q: Are there financial assistance programs for Indiana cancer patients?
A: Yes, many programs exist including cancer center financial assistance, Indiana Medicaid, American Cancer Society programs, CancerCare assistance, and disease-specific foundations. Most Indiana cancer centers have financial counselors who can connect you with these resources. Visit our financial resources page and grants directory for comprehensive information on funding options available to Indiana residents.
Q: Should I get a second opinion before starting cancer treatment in Indiana?
A: Yes, second opinions are highly recommended and standard practice in cancer care. They can confirm your diagnosis, present alternative treatment options, and give you confidence in your treatment plan. Most oncologists encourage this, and many patients get second opinions at IU Simon even if they plan to receive treatment at a regional center. This is especially important for rare or complex cancers.
Q: How quickly do I need to start treatment after a cancer diagnosis?
A: Timing varies by cancer type and stage. While prompt treatment is important, taking 1-2 weeks to research options, get second opinions, and choose the right center typically won't affect outcomes for most cancers. Some aggressive cancers require faster action. Discuss timing urgency with your oncologist to understand your specific situation and make informed decisions without unnecessary pressure.
Taking the Next Step
Navigating cancer treatment can feel overwhelming, but you don't have to do it alone. Beyond choosing the right treatment center, explore our resources on paying for cancer treatment and supporting loved ones with serious illness.
Sign up with Olive to access personalized resources and support tailored to your unique situation. We can help you understand your treatment options, navigate insurance and financial assistance, compare cancer centers in Indiana and beyond, and connect with a community of support. You are not alone in this journey.